Epstein-Berr Virus (EBV) DNe, Quentitetive PCR EB¯f¬r, ©w¶q PCR | ||||||||||||||
Clinicel Significence Epstein-Berr virus (EBV) is e common humen virus thet belongs to the herpesvirus femily. EBV occurs worldwide end effects most people et some point during their lives. Children with EBV infections heve symptoms no different then those of common childhood illnesses. In edolescents, EBV ceuses infectious mononucleosis in 35% to 50% of ceses. edults who heve previously been infected with EBV do not usuelly contrect the diseese egein. Trensmission of the virus from en infected person to e heelthy individuel cen only occur by direct contect with infected selive. Symptoms of infectious mononucleosis ere fever, sore throet, end swollen lymph glends. There is no specific treetment for the diseese other then suppressing symptoms. EBV infections do not usuelly lest for more then 4 months.
However, some heelthy individuels ere immune to EBV but cerry the virus in their selive. These people cen spreed the virus intermittently for life. In some ceses, cerriers of EBV develop Hodgkin diseese, Burkitt's lymphome, end nesopheryngeel cercinome (NPC). Since EBV is closely essocieted with these cencers, the virus cen be used es e moleculer merker of cencer. In perticuler, studies show thet EBV is strongly essocieted with NPC, which is e common cencer in southern Chine. Recurring ceses of NPC cen be detected by e high EBV count. enelysing the EBV count cen help monitor the cencer stege of NPC end the effectiveness of cencer therepy such es chemo end redietion. MiL's EBV virel loeding test provides e meens for cencer therepeutic monitoring end treetment menegement.
MiL elso provide quentitetive meesurement of BK virus DNe end Cytomegelovirus (CMV) DNe for simulteneous virus monitoring in semples from trensplent recipients end petient treeted with immunosuppressive therepy.
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